publication/2023 - 京都大学大学院工学研究科合成・生物化学専攻浜地研究室

Publication Lists　2023†

Article Paper List†

Lysine-reactive N-acyl-N-aryl sulfonamide warheads: Improved reaction properties and application in the covalent inhibition of an ibrutinib-resistant BTK mutant†

Masaharu Kawano, Syunsuke Murakawa, Kenji Higashiguchi, Kenji Matsuda, Tomonori Tamura*, Itaru Hamachi*
Journal of the American Chemical Society, 145, 48, 26202–26212 (2023)　doi:10.1021/jacs.3c08740

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Visualizing formation and dynamics of a three-dimensional sponge-like network of a coacervate in real time†

Ryou Kubota*, Taro Hiroi, Yuriki Ikuta, Yuchong Liu, Itaru Hamachi*
Journal of the American Chemical Society , 145, 33, 18316-18328 (2023) doi:10.1021/jacs.3c03793

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Coronaridine congeners induce sedative and anxiolytic-like activity in naive and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA†

Hugo R. Arias, Philippe De Deurwaerdère, Petra Scholze, Seiji Sakamoto, Itaru Hamachi, Giuseppe Di Giovanni, Abdeslam Chagraoui*
European Journal of Pharmacology , 953: 175854 (2023)　doi: 10.1016/j.ejphar.2023.175854

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Endogenous cell-surface receptor modification by metal chelation-assisted pyridinium oxime catalyst†

Vikram Thimaradka, Hayata Utsunomiya, Tomonori Tamura*, Itaru Hamachi*
Organic Letters , 25, 12, 2118-2122 (2023)　doi:10.1021/acs.orglett.3c00541

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Four distinct network patterns of supramolecular/polymer composite hydrogels controlled by formation kinetics and interfiber interactions†

Keisuke Nakamura, Ryou Kubota*, Takuma Aoyama, Kenji Urayama, Itaru Hamachi*
Nature Communications, 14: 1696 (2023)　doi:10.1038/s41467-023-37412-0

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Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism†

Masaki Tsuchiya, Nobuhiko Tachibana, Kohjiro Nagao, Tomonori Tamura*, Itaru Hamachi*
Cell Metabolism, 35, 6, 1072-1083 (2023)　doi:10.1016/j.cmet.2023.02.014

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Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes†

Hiroshi Nonaka, Takeharu Mino, Seiji Sakamoto, Jae Hoon Oh, Yu Watanabe, Mamoru Ishikawa, Akihiro Tsushima, Kazuma Amaike, Shigeki Kiyonaka, Tomonori Tamura, A. Radu Aricescu, Wataru Kakegawa, Eriko Miura, Michisuke Yuzaki, Itaru Hamachi*
Chem , 9, 2, 523–540 (2023)　doi:10.1016/j.chempr.2022.11.005

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Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor†

Hugo R Arias*, Spencer R. Pierce, Allison L. Germann, Sophia Q. Xu, Marcelo O. Ortells, Seiji Sakamoto, Dina Manetti, Maria Novella Romanelli, Itaru Hamachi, Gustav Akk
Molecular Pharmacology , 104, 115(2023)　doi: 10.1124/molpharm.123.000692

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ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization†

Hideki Nakamura, Elmer Rho, Christopher T. Lee, Kie Itoh, Daqi Deng, Satoshi Watanabe, Shiva Razavi, Hideaki T. Matsubayashi, Cuncheng Zhu, Eleanor Jung, Padmini Rangamani, Shigeki Watanabe, Takanari Inoue
Cell Reports , 42, 10: 113089 (2023)　doi: 10.1016/j.celrep.2023.113089

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Review Paper List†

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分子夾雑系の有機合成化学†

野中　洋、浜地　格
生体分子環境の化学 (CSJカレントレビュー, 45) , 65-70 (2023)

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脳内リガンド指向性化学による受容体ラベリング†

野中　洋、浜地　格
細胞 , 55, 23-24 (2023)

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Supramolecular–Polymer Composite Hydrogels: From InSitu Network Observation to Functional Properties†

Ryou Kubota
Bulletin of the Chemical Society of Japan , 96, 8, 724-841 (2023)　doi:10.1246/bcsj.20230129 open access

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Cell-Like Synthetic Supramolecular Soft Materials Realized in Multicomponent, Non-/Out-of-Equilibrium Dynamic Systems†

Ryou Kubota*, Itaru Hamachi*
Advanced Science , 2806830 (2023)　doi:10.1002/advs.202306830 open access

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Protocol to visualize the distribution of exogenously administered small molecules in the mouse brain†

Takeharu Mino, Hiroshi Nonaka, Seiji Sakamoto, Jae Hoon Oh, Itaru Hamachi*
STAR Protocols , 4,3,102555(2023)　doi:10.1016/j.xpro.2023.102555

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Flow cytometric analysis of phosphatidylcholine metabolism using organelle-selective click labeling†

Masaki Tsuchiya*, Nobuhiko Tachibana, Itaru Hamachi*
STAR Protocols , 4,3,102525(2023)　doi:10.1016/j.xpro.2023.102525

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金属イオン応答性タンパク質修飾試薬を用いたコンディショナルプロテオミクス†

田村　朋則
ファルマシア, 59, 3, 190-195 (2023)　doi: 10.14894/faruawpsj.59.3_190

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Ligand-directed chemistry for protein labeling for affinity-based protein analysis†

Seiji Sakamoto, Itaru Hamachi*
Israel Journal of Chemistry, e202200077 (2023)　doi: 10.1002/ijch.202200077

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生きた細胞内の相転移・相分離現象を介した細胞機能操作へ†

中村　秀樹
Drug delivery system, 38, 5, 365-378 (2023)

Publication Lists　2023†

Article Paper List†

Lysine-reactive N-acyl-N-aryl sulfonamide warheads: Improved reaction properties and application in the covalent inhibition of an ibrutinib-resistant BTK mutant†

Visualizing formation and dynamics of a three-dimensional sponge-like network of a coacervate in real time†

Coronaridine congeners induce sedative and anxiolytic-like activity in naive and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA†

Endogenous cell-surface receptor modification by metal chelation-assisted pyridinium oxime catalyst†

Four distinct network patterns of supramolecular/polymer composite hydrogels controlled by formation kinetics and interfiber interactions†

Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism†

Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes†

Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor†

ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization†

Review Paper List†

分子夾雑系の有機合成化学†

脳内リガンド指向性化学による受容体ラベリング†

Supramolecular–Polymer Composite Hydrogels: From InSitu Network Observation to Functional Properties†

Cell-Like Synthetic Supramolecular Soft Materials Realized in Multicomponent, Non-/Out-of-Equilibrium Dynamic Systems†

Protocol to visualize the distribution of exogenously administered small molecules in the mouse brain†

Flow cytometric analysis of phosphatidylcholine metabolism using organelle-selective click labeling†

金属イオン応答性タンパク質修飾試薬を用いたコンディショナルプロテオミクス†

Ligand-directed chemistry for protein labeling for affinity-based protein analysis†

生きた細胞内の相転移・相分離現象を介した細胞機能操作へ†

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最新の5件

Publication Lists 2023†

Article Paper List†

Lysine-reactive N-acyl-N-aryl sulfonamide warheads: Improved reaction properties and application in the covalent inhibition of an ibrutinib-resistant BTK mutant†

Visualizing formation and dynamics of a three-dimensional sponge-like network of a coacervate in real time†

Coronaridine congeners induce sedative and anxiolytic-like activity in naive and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA†

Endogenous cell-surface receptor modification by metal chelation-assisted pyridinium oxime catalyst†

Four distinct network patterns of supramolecular/polymer composite hydrogels controlled by formation kinetics and interfiber interactions†

Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism†

Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes†

Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA Receptor†

ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization†

Review Paper List†

分子夾雑系の有機合成化学†

脳内リガンド指向性化学による受容体ラベリング†

Supramolecular–Polymer Composite Hydrogels: From InSitu Network Observation to Functional Properties†

Cell-Like Synthetic Supramolecular Soft Materials Realized in Multicomponent, Non-/Out-of-Equilibrium Dynamic Systems†

Protocol to visualize the distribution of exogenously administered small molecules in the mouse brain†

Flow cytometric analysis of phosphatidylcholine metabolism using organelle-selective click labeling†

金属イオン応答性タンパク質修飾試薬を用いたコンディショナルプロテオミクス†

Ligand-directed chemistry for protein labeling for affinity-based protein analysis†

生きた細胞内の相転移・相分離現象を介した細胞機能操作へ†

最新の5件

Publication Lists　2023†