Professor　　　浜地 格　- Itaru Hamachi - †

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Paper List　2020 - †

294. Modulation of the mammalian GABAA receptor by type I and type II positive allosteric modulators of the α7 nicotinic acetylcholine receptor
H. R. Arias, A. L. Germann, S. R. Pierce, S. Sakamoto, M. O. Ortells, I. Hamachi, G. Akk
British Journal of Pharmacology (2022) doi:10.1111/bph.15948

293. Light-induced stabilization of microtubules by photo-crosslinking of Tau-derived peptide
S. Watari, H. Inaba, T. Tamura, A. Md. R. Kabir, A. Kakugo, K. Sada, I. Hamachi, K. Matsuura
Chemical Communications , 58, 9190 - 9193 (2022) doi:10.1039/D2CC01890J

292. Temporal stimulus patterns drive differentiation of a synthetic dipeptide-based coacervate
R. Kubota*, S. Torigoe, I. Hamachi*
Journal of the American Chemical Society , ja-2022-05101r (2022) doi:10.1021/jacs.2c05101

291. Chemical biology tools for imaging-based analysis of organelle membranes and lipids
K. Ojima, W. Kakegawa, T. Yamasaki, Y. Miura, M. Itoh, Y. Michibata, R. Kubota, T. Doura, E. Miura, H. Nonaka, S. Mizuno, S. Takahashi, M. Yuzaki*, I. Hamachi*, S. Kiyonaka*
Nature Communications , 13, 3167 (2022)　doi:10.1101/2021.10.01.462737

290. Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue
T. Tamura, I. Hamachi
Current Opinion in Chemical Biology , accepted (2022)

289. Orthogonal activation of metabotropic glutamate receptor using coordination chemogenetics
A. Senoo, Y. Yamada, K. Ojima, T. Doura, I. Hamachi, S. Kiyonaka
Frontiers in Chemistry , 9, 825669 (2022) doi:10.3389/fchem.2021.825669

288. Extracellular ATP limits homeostatic T cell migration within lymph nodes
D. Kobayashi, Y. Sugiura, E. Umemoto, A. Takeda, H. Ueta, H. Hayasaka, S. Matsuzaki, T. Katakai, M. Suematsu, I. Hamachi, G. G Yegutkin, M. Salmi, S. Jalkanen, M. Miyasaka
Frontiers in Immunology, 12 (2021) doi:10.3389/fimmu.2021.786595

287. Photo-triggered spatially controlled out-of-equilibrium patterns of peptide nanofibers in a self-sorting double network hydrogel
K. Nakamura, W. Tanaka, K. Sada, R. Kubota, T. Aoyama, K. Urayama, I. Hamachi
Journal of the American Chemical Society, 143, 46, 19532–19541(2021) doi:10.1021/jacs.1c09172

286. Organelle-selective labeling of choline-containing phospholipids(CPLs) and real-time imaging in living cells
M. Tsuchiya, T. Tamura, I. Hamachi*
Current Protocols , e105, Volume 1 (2021) doi: 10.1002/cpz1.105

285. Recent applications of N-acyl imidazole chemistry in chemical biology
T. Mino, S. Sakamoto, I. Hamachi*
Bioscience, Biotechnology, and Biochemistry , 85, 1, 53-60 (2021) doi:10.1093/bbb/zbaa026

284. Voices of chemical biology
B. Davis, K. Backus, G. Winter, R. Chica, D. Li, S. Lee, C. He, A. Weeks, C. Overall, S. Hagihara, B. Thuronyi, S. Kamat, L. Chen, R. HurtadoGuerrero, S. Yao, L. Mahal, C. Voigt, C. Woo, E. Strauss, K. Kikuchi, T. Dore, S. Radford, X. Li, W. Heo, G. S. Furga, T. Deans, V. Belousov, M. Matthews, C. Jackson, S. Malek, H. Waldmann, A. Rising, M. Jewett, D. Stamou, E. Parker, M. Murakami, K. Polizzi, I. Hamachi, T. Erb, C. Joo, M. Uesugi, R. Prinjha, G. Rechavi, R. Solano, B. Schulman, Y. David, R. Oslund
Nature Chemical Biology , 17, 1-4 (2021) doi:10.1038/s41589-020-00714-1

283. Microscopic Imaging Techniques for Molecular Assemblies: Electron, Atomic Force, and Confocal Microscopies
R. Kubota, W. Tanaka, I. Hamachi*
Chemical Reviews , (2021)Accepted doi:10.1021/acs.chemrev.0c01334

282. Enhanced Suppression of a Protein–Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead
T. Ueda, T. Tamura, M. Kawano, K. Shiono, F. Hobor, A. J. Wilson, and I. Hamachi*
Journal of the American Chemical Society , 143, 12, 4766–4774(2021) doi.org/10.1021/jacs.1c00703

281. Ligand-directed two-step labeling to quantify neuronal glutamate receptor trafficking
K. Ojima, K. Shiraiwa, T. Doura, M. Takato, K. Komatsu, M. Yuzaki, I. Hamachi*, S. Kiyonaka*
Nature Communications , 12:831 (2021) doi:10.1038/s41467-021-21082-x

280. Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent
V. Thimaradka, J. H. Oh, C. Heroven, A. R. Aricescu, M. Yuzaki, T. Tamura*, I. Hamachi*
Bioorganic & Medicinal Chemistry, , 30, 115947(2021) doi:10.1016/j.bmc.2020.115947

279. Fluorescence imaging of drug target proteins using chemical probes
H. Zhu, I. Hamachi*
Journal of Pharmaceutical Analysis , 10, 5, 426-433 (2020)  doi:10.1016/j.jpha.2020.05.013

278. Chemical Tools for Endogenous Protein Labeling and Profiling
K. Shiraiwa, R. Cheng, H. Nonaka, T. Tamura, and I. Hamachi*
Cell Chemical Biology , 27, 8, 970-985(2020) doi:10.1016/j.chembio|.2020.06016

277. In Situ Real-time Confocal Imaging of a Self-assembling Peptide-grafted Polymer Showing pH-responsive Hydrogelation
R. Kubota, S. Torigoe, S. Liu, & I. Hamachi*
Chemistry Letters , 49, 11, 1319-1323(2020) doi:10.1246/cl.200513

276. Organelle membrane-specific chemical labeling and dynamic imaging in living cells
T. Tamura, A. Fujisawa, M. Tsuchiya, Y. Shen, K. Nagao, S. Kawano, Y. Tamura, T. Endo, M. Umeda & I. Hamachi*
Nature Chemical Biology , 16, 12, 1361-1367(2020) doi:10.1038/s41589-020-00651-z

275. Imaging and profiling of proteins under oxidative conditions in cells and tissues by hydrogen-peroxide-responsive labeling
H. Zhu, T. Tamura, A. Fujisawa, Y. Nishikawa, R. Cheng, M. Takato, and I. Hamachi*
Journal of the American Chemical Society , 142, 37, 15711–15721(2020) doi:10.1021/jacs.0c02547

274. Control of seed formation allows two distinct self-sorting patterns of supramolecular nanofibers
R. Kubota, K. Nagao, W. Tanaka, R. Matumura, T. Aoyama, K. Urayama and I. Hamachi*
Nature Communications , 11, 1, 4100(2020) doi:10.1038/s41467-020-17984-x

273. Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper
S. Lee, Y. S. C. Chung, P. Liu, L. Craciun, Y. Nishikawa, K. Bruemmer, I. Hamachi, K. Saijo, E. Miller, C. Chang*
Journal of the American Chemical Society , 142, 35, 14993–15003(2020) doi:10.1021/jacs.0c05727

272. Protein-Responsive Protein-Release of Supramolecular/polymer Hydrogel Composite Integrating Enzyme Activation Systems
H. Shigemitsu, R. Kubota, K. Nakamura, T. Matsuzaki, S. Minami, T. Aoyama, K. Urayama and I. Hamachi*
Nature Communications , 11, 1, 3859(2020) doi:10.1038/s41467-020-17698-0

271. Force generation by a propagating wave of supramolecular nanofibers
R. Kubota, M. Makuta, R. Suzuki, M. Ichikawa, M. Tanaka and I. Hamachi*
Nature Communications, 11, 1, 3541(2020) doi:10.1038/s41467-020-17394-z

270. Fluorescence determination of soluble pyrophosphate levels in synovial fluid as a marker of pseudogout using middle point of quantification concept and molecular sensor
N. Yongwattana, N. Mekjinda, W. Thepsing, S. Ounsuk, P. Wongkongkatep, T. Tawonsawatruk, I. Hamachi, A. Ojida, J. Wongkongkatep*
Science Asia , 46, 36-42 (2020)　doi:10.2306/scienceasia1513-1874.2020.S005

269. Fluorescence Differentiation of ATP-Related Multiple Enzymatic Activities in Synovial Fluid as a Marker of Calcium Pyrophosphate Deposition Disease Using Kyoto Green
N. Yongwattana, N. Mekjinda,T. Tawonsawatruk, I. Hamachi, A. Ojida and J. Wongkongkatep*
molecules, 25, 1116 (2020)　doi:10.3390/molecules25051116

268. Screening of protein-ligand interactions under crude conditions by native mass spectrometry
K. Takano, S. Arai, S. Sakamoto, H. Ushijima, T. Ikegami, K. Saikusa, T. Konuma, I. Hamachi, S. Akashi
Analytical and Bioanalytical Chemistry , 412, 4037-4043 (2020)　doi:10.1007/s00216-020-02649-x

267. Masking Phosphate with Rare-Earth Elements Enables Selective Detection of Arsenate by Dipycolylamine-ZnII Chemosensor
N. Mekjinda, S. Phunnarungsi, V. Ruangpornvisuti, R. Ritchie, I. Hamachi, A. Ojida, J. Wongkongkatep
Scientific Reports , 10:2656 (2020)　doi:10.1038/s41598-020-59585-0

266. Development of a Photoactivatable Proximity Labeling Method for the Identification of Nuclear Proteins
T. Tamura*, M. Takato, K. Shiono, I. Hamachi*
Chemistry Letters , 49, 145-148 (2020)　doi:10.1246/cl.190804

265. The Power of Confocal Laser Scanning Microscopy in Supramolecular Chemistry: In situ Real‐time Imaging of Stimuli‐Responsive Multicomponent Supramolecular Hydrogels
R. Kubota, K. Nakamura, S. Torigoe, I. Hamachi
ChemistryOPEN , 9,67-79 (2020)　doi:10.1002/open.201900328

264. Development of a cell-based ligand-screening system for identifying Hsp90 inhibitors
T. Ueda, T. Tamura*, I. Hamachi*
Biochemistry , 59, 2, 179-182 (2020)　doi:10.1021/acs.biochem.9b00781

 
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