## Research †

### Classification of Reaction Integration †

The way of integration of reactions can be classified into three types;

(a) **Time and space integration**, where all reaction components are mixed at once to perform a sequence of reactions in one-pot (domino, tandem, or cascade reactions).

**time and space integration**

(b) **Time integration**, where a sequence of reactions is conducted in one-pot by adding components at intervals (one-pot sequential synthesis).

**time integration**

(c) **Space integration**, where a sequence of reactions is conducted in one flow by adding components at different places (flow synthesis).

**space integration**