Professor   浜地 格 - Itaru Hamachi -

Paper List 1990 - 1999

58. Chemical Modification of Structures and Functions of Proteins by Cofactor Reconstitution Method
I. Hamachi, S. Shinkai
Eur. J. Org. Chem., 3, 539-549 (1999)

57. Ru(bpy)3-Based Artificial Receptors toward a Protein Surface: Selective Binding and Efficient Photoreduction of Cytochrome c
H. Takashima, S. Shinkai, I. Hamachi
Chem. Commun., 23, 2345-2346 (1999)

56. Metal-Induced Conformational Changes in Calix[n]arenes Can Control the Electron-Transfer Efficiency between Porphyrin and [60]Fullerene in an On-Off Manner
M. Kawaguchi, A. Ikeda, I. Hamachi, S. Shinkai
Tetrahedron. Lett., 40, 8245-8249 (1999)

55. Electron Transfer from Zn-Protoporphyrin IX to Ruthenium Ammine Attached at His63 of Reconstituted Cytochrome b562
I. Hamachi, H. Takashima, S. Tsukiji, S. Shinkai, T. Nagamune, S. Oishi
Chem. Lett., 7, 551-552 (1999)

54. Direct Observation of the Ferric-Porphyrin Cation Radical as an Intermediate in the Phototriggered Oxidation of Ferric- to Ferryl-Heme Tethered Ru(bpy)3 in Reconstituted Myoglobin
I. Hamachi, S. Tsukiji, S. Shinkai, S. Oishi
J. Am. Chem. Soc., 121, 5500-5506 (1999)

53. A Convenient Synthesis of a Ru(bpy)3-Based Catenane-Type Triad and Its Incorporation into a Protein Scaffold
Y-Z. Hu, S. Tsukiji, S. Shinkai, I. Hamachi
Chem. Lett., 6, 517-518 (1999)

52. Single- or Dual-Mode Switching of Semisynthetic Ribonuclease S' with an Iminodiacetic Acid Moiety in Response to the Copper(II) Concentration
I. Hamachi, Y. Yamada, T. Matsugi, S. Shinkai
Chem. -A Euro. J., 5, 1503-1511 (1999)

51. Design and Semisynthesis of Spermine-Sensitive Ribonuclease S'
I. Hamachi, Y. Yamada, R. Eboshi, T. Hiraoka, S. Shinkai
Bioorg. Med. Chem. Lett., 9, 1215-1218 (1999)

50. Facile Preparation of Robust Organic Gels by Cross-Link of a Sugar-Integrated Gelator by Toluene-2,4-diisocyanate
K. Inoue, Y. Ono, Y. Kanekiyo, S. Kiyonaka, I. Hamachi, S. Shinkai
Chem. Lett., 3, 225-226 (1999)

49. A Boronic Acid-diol Interaction Is Useful for Chiroselective Transcription of the Sugar Structure to the Delta- versus Lamda-[Co(III)(bpy)3]3+ Ratio
T. Mizuno, Takeuchi, I. Hamachi, K. Nakashima, S. Shinkai
J. Chem. Soc., Perkin Trans. 2, 10, 2281-2288 (1998)

48. Design and Semisynthesis of Photo-Active Myoglobin-Bearing Ruthenium Tris(2,2-bipyridine) Using Cofactor-Reconstitution
I. Hamachi, S. Tanaka, S. Tsukiji, S. Shinkai, S. Oishi
Inorg. Chem., 37, 4380-4388 (1998)

47. Photoswiching of the Enzymatic Activity of Semisynthetic Ribonuclease S' Bearing Phenylazophenylalanine at a Specific Site
I. Hamachi, T. Hiraoka, Y. Yamada, S. Shinkai
Chem. Lett., 6, 537-538 (1998)

46. Pyrenylboronic Acids as a Novel Entry for Photochemical DNA Cleavage: Diradical-Forming Pyrene-1,6-diyldiboronic Acid Mimics the Cleavage Mechanism of Enediyne Antitumor Antibiotics
H. Suenaga, K. Nakashima, T. Mizuno, M. Takeuchi, I. Hamachi, S. Shinkai
J. Chem. Soc., Perkin Trans. 1, 7, 1263-1267 (1998)

45. Design and Synthesis of a Transition Metal Responsive Semisynthetic Myoglobin-Bearing Iminodiacetic Acid Moiety
I. Hamachi, T. Matsugi, K. Wakigawa, S. Shinkai
Inorg. Chem., 37, 1592-1597 (1998)

44. Incorporation of an Artificial Receptor into a Native Protein: New Strategy for the Design of Semisynthetic Enzymes with Allosteric Properties
I. Hamachi, T. Nagase, Y. Tajiri, S. Shinkai
Bioconjugate Chem., 8, 862-868 (1997)

43. Protein Engineering Using Molecular Assembly: Functional Conversion of Cytochrome c via Noncovalent Interactions
I. Hamachi, A. Fujita, T. Kunitake
J. Am. Chem. Soc., 119, 9096-9102 (1997)

42. Chiroselective Transcription of the Sugar Structure to D- or L-[CoIII(bpy)3]3+ Using a Boronic Acid-Sugar Template Interaction
T. Mizuno, M. Takeuchi, I. Hamachi, K. Nakashima, S. Shinkai
Chem. Commun., 18, 1793-1794 (1997)

41. Photocontrol of the Redox State of Ruthenium-Tris(bipyridine)-Appended Cytochrome b562
I. Hamachi, S. Tanaka, S. Tsukiji, S. Shinkai, M. Shimizu, T. Nagamune
Chem. Commun., 18, 1735-1736 (1997)

40. Design and Synthesis of Sugar-Responsive Semiartificial Myoglobin Triggered by Modulation of Apoprotein-Cofactor Interactions
I. Hamachi, Y. Tajiri, T. Nagase, S. Shinkai
Chem. -A Euro. J., 3, 1025-1031 (1997)

39. Pyrenylboronic Acid as a Novel Entry for Photochemical DNA Cleavage
H. Suenaga, K. Nakashima, I. Hamachi, S. Shinkai
Tetrahedron Lett., 38, 2479-2482 (1997)

38. A Novel Sugar Sensing System Designed with a Cooperative Action of a Boronic-Acid-Appended Zinc Porphyrin and a 3-Pyridylboronic Acid Axial Ligand
M. Takeuchi, H. Kijima, I. Hamachi, S. Shinkai
Bull. Chem. Soc. Jpn., 70, 699-705 (1997)

37. Sugar-Induced Chiral Orientation of Boronic-Acid-Appended Amphiphile Clusters Formed in the Dipalmitoylphosphatidylcholine (DPPC) Membrane
T. Kimura, M. Takeuchi, I. Hamachi, S. Shinkai
Israel J. Chem., 36, 379-388 (1996)

36. Transition-Metals Facilitated Electron Transfer of Semisynthetic Myoglobin Bearing Bis(iminodiacetic Acid) Moiety
I. Hamachi, T. Matsugi, S. Shinkai
Tetrahedron Lett., 37, 9233-9236 (1996)

35. Sugar-Enhanced Aniline Hydroxylase Activity of Semisynthetic Myoglobins Possessing m-Dihydroxyphenylalanine
I. Hamachi, T. Nagase, Y. Tajiri, S. Shinkai
Chem. Commun., 18, 2205-2206 (1996)

34. Efficient Photogeneration of Oxidizing (Compound II-like) Species of Semisynthetic Myoglobin Appending Ruthenium Tris(2,2'-bipyridine)
I. Hamachi, S. Tsukiji, S. Tanaka, S. Shinkai
Chem. Lett., 9, 751-752 (1996)

33. Facilitated Photoreduction of Ruthenium Bis(4'-methylterpyridine) Pendant Myoglobin
I. Hamachi, T. Matsugi, S. Tanaka, S. Shinkai
Bull. Chem. Soc. Jpn., 69, 1657-1661 (1996)

32. Aniline-Hydroxylase Activity of Myoglobin by Coupling with a Membrane-Bound Electron Transport System
I. Hamachi, A. Fujita, T. Kunitake
Chem. Lett., 8, 657-658 (1995)

31. Peroxidase Activity of Cytochrome c Generated by Phenylboronic Acid Modification
I. Hamachi, O. Kimura, H. Takeshita, S. Shinkai
Chem. Lett., 7, 529-530 (1995)

30. X-ray Crystallographic Studies of a Mn(II)-Bridged Biscalix[4]arene with a Large Inner Cavity
H. Iki, H. Tsuzuki, H. Kijima, I. Hamachi, S. Shinkai
Supramol. Chem., 4, 223-228 (1995)

29. Enhanced N-Demethylase Activity of Cytochrome c Bound to a Phosphate-Bearing Synthetic Bilayer Membrane
I. Hamachi, A. Fujita, T. Kunitake
J. Am. Chem. Soc., 116, 8811-8812 (1994)

28. Novel Chemical Modification of Myoglobin by an Alcohol-Responsive Phenylboronic Acid Function
T. Nagasaki, O. Kimura, I. Hamachi, S. Shinkai
Chem. Lett., 10, 1945-1948 (1994)

27. Sugar-Responsive Semisynthetic Myoglobin Bearing Phenylboronic Acid Groups as Recognition Sites
I. Hamachi, Y. Tajiri, S. Shinkai
J. Am. Chem. Soc., 116, 7437-7438 (1994)

26. Enhanced Peroxidase Activity of Cytochrome c by Phosphate Bilayer Membrane
A. Fujita, H. Senzu, T. Kunitake, I. Hamachi
Chem. Lett., 7, 1219-1232 (1994)

25. Sugar Sensing Utilizing Aggregation Properties of Boronic-Acid-Appended Porphyrins and Metalloporphyrins
H. Murakami, T. Nagasaki, I. Hamachi, S. Shinkai
J. Chem. Soc. Perkin Trans. 2, 975-981 (1994)

24. Self-Sufficient Electron Injection from NADH to the Active Center of Flavin-Pendant Myoglobin
I. Hamachi, K. Nomoto, S. Tanaka, Y. Tajiri, S. Shinkai
Chem. Lett., 6, 1139-1142 (1994)

23. Synthesis, Metal-Binding Properties and Polypeptide Solubilization of 'Crowned' Arborols
T. Nagasaki, O. Kimura, M. Ukon, S. Arimori, I. Hamachi, S. Shinkai
J. Chem. Soc. Perkin Trans. 1, 75-81 (1994)

22. Sugar-Facilitated Incorporation of a Heme Cofactor Bearing Phenylboronic Acid Groups into Apomyoglobin
I. Hamachi, Y. Tajiri, H. Murakami, S. Shinkai
Chem. Lett., 3, 575-578 (1994)

21. Sugar Sensing Utilizing Aggregation Properties of a Boronic-Acid-Appended Porphyrin
H. Murakami, T. Nagasaki, I. Hamachi, S. Shinkai
Tetrahedron Lett., 34, 6273-6276 (1993)

20. Light-Driven Activation of Reconstituted Myoglobin with a Ruthenium Tris(2,2'-bipyridine) Pendant
I. Hamachi, S. Tanaka, S. Shinkai
J. Am. Chem. Soc., 115, 10458-10459 (1993)

19. Energy Transfer from Zinc-Myoglobin to a Cyanine Dye Facilitated by Their Simultaneous Binding to a Phosphate Bilayer Membrane
I. Hamachi, H. Fujimura, T. Kunitake
Chem. Lett., 22, 1551-1554 (1993)

18. Reconstitution of Myoglobin with a Heme Cofactor Bearing a Ruthenium Tris(2,2'-bipyridine) Pendant
I. Hamachi, S. Tanaka, S. Shinkai
Chem. Lett., 22, 1417-1420 (1993)

17. Lipid Anchored Myoglobin 2. Effect of the Anchor Structure on Membrane Binding
I. Hamachi, S. Higuchi, K. Nakamura, H. Fujimura, T. Kunitake
Chem. Lett., 22, 1175-1178 (1993)

16. Anisotropic Incorporation of Lipid-Anchored Myoglobin into a Phospholipid Bilayer Membrane
I. Hamachi, K. Nakamura, A. Fujita, T. Kunitake
J. Am. Chem. Soc., 115, 4966-4970 (1993)

15. Simultaneous Fixation of Orientation of Myoglobin and Metalloporphyrins by Synthetic Bilayer Membrane
I. Hamachi, S. Noda, H. Iwasaki, T. Kunitake
Proc. Japan Acad., 68, 47-50 (1992)

14. Functional Conversion of Myoglobin Bound to Synthetic Bilayer Membranes: From Dioxygen Storage Protein to Redox Enzyme
I. Hamachi, S. Noda, T. Kunitake
J. Am. Chem. Soc., 113, 9625-9630 (1991)

13. Immobilization of Myoglobin in a Multilayer Film of Two-Dimensional Polymer Network
I. Hamachi, H. Fujimura, T. Kunitake,
Chem. Lett., 20, 2227-2230 (1991)

12. A Novel Transmembrane Electron Channel Containing Flavin Units
Y. Kobuke, M. Yamanishi, I. Hamachi, H. Kagawa, H. Ogoshi
J. Chem. Soc., Chem. Commun., 13, 895-897 (1991)

11. Oriented Intercalation of Myoglobin into Multilayered Films of Synthetic Bilayer Membranes
I. Hamachi, T. Honda, S. Noda, T. Kunitake
Chem. Lett., 20, 1121-1124 (1991)

10. Layered Arrangement of Oriented Myoglobins in Cast Films of a Phosphate Bilayer Membrane
I. Hamachi, S. Noda, T. Kunitake
J. Am. Chem. Soc., 112, 6744-6745 (1990)

 


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